![]() Stone, PharmD, and Emily Evans, PharmD, who round daily with the multidisciplinary The program’s key players are the two NICU pharmacists, Sadie Meanwhile, the rate of patients with AKI who had also been exposed to nephrotoxic medications fell 64%, while patients spent 68% fewer days in AKI. In the 18 months after implementing the program, nephrotoxic medication exposure dropped 42% and AKI prevalence fell 78%, she said. The Baby NINJA project at Children’s has demonstrated similarly stellar outcomes, noted Christine Stoops, D.O., assistant professor of pediatrics at the University of Alabama at Birmingham (UAB) and the primary investigator on the initiative. As a result, last year it was added to the Solutions for Patient Safety consortium and instituted at 147 children’s hospitals worldwide. The NINJA initiative reduced exposure to nephrotoxic medications by 38% and concomitant AKI by 64%. ![]() Kidney function was closely monitored for any signs of AKI. Medications that they needed for as long as they needed them, and that their To ensure that children only receive the nephrotoxic Hospital Medical Center that started in 2011 in non-critically ill children. The effort builds off the NINJA (Nephrotoxic Injury Negated by Just-in-TimeĪction) project, a joint endeavor between Children’s and the Cincinnati Children’s So successful it is now being validated at several other major children’s To address this problem, in 2015 Children’s ofĪlabama began the first initiative in the country designed to reduce the use of ,, There is also evidence that even a single incidence of AKI increases the risk of chronic kidney disease. About 1 in 4 of those experience at least one episode of acute kidney injury (AKI), which can lead to increased length of stay and mortality. ![]() ![]() ![]() Up to 87% of very low-birthweight infants in the neonatal intensive care unit (NICU) are exposed to at least one nephrotoxic medication during their stay. ![]()
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